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Graphene: The Future of Neural Electrodes?




The neural electrode technique is a powerful tool for monitoring and regulating neural activity, which has a wide range of applications in basic neuroscience and the treatment of neurological diseases. One of the most significant challenges in using neural electrodes is finding materials that have good biocompatibility, low impedance, and high charge injection capacity for long-term stable recording and regulation. Conventional neural electrodes made of hard materials like metals and semiconductors usually don't match the mechanical properties of soft neural tissues, leading to inflammation and reducing the long-term stability of neural signal recording.


However, graphene-based nanomaterials have shown promise as a solution to this challenge. Graphene has excellent flexibility, biocompatibility, and electrical conductivity, making it an ideal material for nerve probes. The high mechanical flexibility of graphene allows it to closely conform to soft brain tissues and form a stable electrode-nerve interface. Additionally, its high electrical conductivity and carrier mobility make it an attractive option for neural recording and regulation.


In this literature review, the authors discuss the various graphene-based electrodes and their potential applications in neural activity detection. They also touch upon the biological safety of graphene neural electrodes, related challenges, and their prospects.


Overall, the development of graphene-based neural electrodes represents a cost-effective and promising solution to improve the biocompatibility and long-term stability of neural interfaces.


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